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In a small number of cases people who take Lamictal or some other anticonvulsance can develop a deadly rash named Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) (a more severe version). Again this is rare. However, if you develop a rash, here is a description of SJS leisions.
If you this there is even a small rash is related to this syndrom see a doctor immediately and tell them what medications you are on. Again, without treatment this can kill you.
1. The rash begins as a round erythematous papule, which enlarges up to 1 to 2 cm over 24 to 48 hours. The periphery of the lesion is erythematous and raised or edematous. The center becomes more cyanotic looking and can be white/yellow or gray. This is the pathognomonic “target lesion,” but it may not be present in all cases. If a blister forms in the middle, the term “iris lesion” is more appropriate.2. Lesions are generally symmetrical, with acral to central spread including extensor surfaces, face, palms, and soles. Mucosal lesions indicate a more severe type; bullae with sloughing in large sheets suggests TEN.
Natasha Tracy is an award-winning writer, speaker, advocate, and consultant from the Pacific Northwest. She has been living with bipolar disorder for 26 years and has written more than 2000 articles on the subject.
Find more of Natasha’s work in her acclaimed book: "Lost Marbles: Insights into My Life with Depression & Bipolar" on Amazon.
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I’m in my third week of being weaned off of seroquel after taking for approximately 8 years. This has been an experience I have never been through & I wouldn’t wish this on anybody. Pure hell. My appetite is all but gone. Must force myself to eat. Whole digestive system gone awry. Please, before you can be prescribed this dangerous medication, do your reasearch, which I sadly did not do. I’ve got 2 more days to go, before I’m totally weaned off. Praise God for his infinite healing.
Hi Susan,
I’m sorry you’re having such a difficult time with weaning off that medication. I know that getting off a medication can be difficult.
For anyone interested, I wrote this about getting off medication. (It’s specifically about antidepressants, but it is relevant to medication in general.) https://staging.natashatracy.com/treatment-issues/withdrawal/stop-antidepressants-minimize-withdrawal/
Antipsychotics are actually one of the easier meds to wean off of for most people. I’m so sorry that hasn’t been your experience.
I hope you regain some wellness soon.
— Natasha Tracy